There will be affect on the bike or the ABS braking system. Happens a lot with pre 09 Gold Wings to correct the speedo.
ABS works in a panic stop by identifying if a wheel is about to lock up when you press the brake pedal, it does that by detecting a rapid deceleration in speed, than allows the force of the brake fluid going to that wheel to be lightened so it will not lock up, that is why you will feel a pulsing sensation in the brake pedal when the ABS is activated.
Look at all the cars and SUV's on the road with ABS and run different size tires than the stock size.