a google search will lead to normal temps during October.
There are many days in July when a windbreaker or jacket feels good so I would take layers you can add and subtract as needed. I suspect you will be looking at anything from the 50's t the low 70's.
Assuming you will ride the Dragon, stop at Deal's Gap. They have maps with about 10 routes that include sites to see along the way.
Gattlinburg is a nice town to relax and shop. There is a huge outlet mall if someone needs a shopping fix.
Cherokee is not far if you want to check your luck at the casino.
I would also start a Carolina Kitchen in Robbinsville. When you get to town, you will see Mikey D's. It is just ahead on the right coming from 2 Whl Inn.
Many, many great rides and sites. You won't get to them all so again, I would get a map at Deal's Gap, it is for bikers.
There is a beautiful Parkway than runs for many miles along a stream, a dam, waterfalls take your pick. Maggie Valley, Hwy 321 is a blast no matter where you find it.